Acute Bacterial Meningitis

Medicine, Infectious

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Data 2fimages 2fn2m6k26oqail6wj6kova 190311 s0 mushtaq saima acute bacterial meningitis intro
04:23
Acute Bacterial Meningitis
Data 2fimages 2fudvwy8wsggfa7j4o2jla 190311 s1 mushtaq saima etiologic factors
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Etiologic Factors
Data 2fimages 2f0iq9huikqro4cl3nzg98 190311 s2 mushtaq saima pathophysiology
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Pathophysiology
Data 2fimages 2fjofqk21zt1udkus0jpeq 190311 s3 mushtaq saima clinical presentation
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Clinical Presentation
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Diagnosis
Data 2fimages 2fdjckpkgwq1porbxqinpn 190311 s5 mushtaq saima treatment and prognosis
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Treatment and Prognosis

Lecture´s Description

For an in depth elucidation of acute bacterial meningitis, watch this medical video lecture on sqadia.com. This V-learning lecture allows you to have a deep understanding of meningitis of bacterial origin. Our medical specialist comprehensively talks about causative agents of meningitis, how the disease progress and reach a serious stage. Likewise, the clinical presentation is also discussed along with the diagnosis via broad-based bacterial polymerase chain reaction, latex agglutination. Dr. Saima Mushtaq also sheds light on treatment option which can be done through empirical antimicrobial therapy, specific antimicrobial therapy, and adjunctive therapy.

Etiologic Factors

Amongst the various acute infections of nervous system, acute bacterial meningitis is discussed primarily in this section. Meninges, subarachnoid space, and brain parenchyma are involved in meningoencephalitis. Epidemiologically, organisms responsible for causing the disease are elaborated. Our medical specialist explains etiologic factors in detail.

Pathophysiology

Initially, Dr. Saima Mushtaq talks about common causative organisms along with the pathophysiology.  Then light is shed upon pathogenesis in which critical event, neurologic manifestations, and neurologic injury is discussed. Next, induction of inflammatory response, chemokines and cytokines comes under consideration. Medical specialist at sqadia.com V-learning also explains the early stages of meningitis.

Clinical Presentation

Clinical triad of meningitis follows fever, headache, and nuchal rigidity. Initial presentation is the seizures which is of two types i.e. focal seizures and generalized seizure. Signs of increased intracranial pressure are discussed later on. Meningococcemia and skin lesions are the clues to the diagnosis. Dr. Saima Mushtaq gives an insight to neurologic complications of bacterial meningitis through a detailed flowchart.

Diagnosis

Diagnosis is carried out by obtaining blood cultures, empirical antimicrobial therapy. Alongside, CSF glucose concentrations is highlighted. Broad-based bacterial polymerase chain reaction detects small numbers of viable and nonviable organisms. Latex agglutination (LA) test, Limulus Amebocyte Lysate Assay are also considered. Information about rocky mountain spotted fever is also given. Moreover, Dr. Saima Mushtaq notify about ehrlichiosis, focal suppurative CNS infections and non-infectious CNS disorders.

Treatment and Prognosis

Empirical antimicrobial therapy, specific antimicrobial therapy, and adjunctive therapy are the treatment options for acute bacterial meningitis. For pneumococcal meningitis, therapy can be modified. Listeria meningitis can be treated by giving ampicillin for at least 3 weeks. Treatment of staphylococcal meningitis, gram-negative bacillary meningitis, and increased intracranial pressure is also elaborated in detail. Information about prognosis is also enlightened.

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