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Bacterial DNA History
In this lecture ´´Bacterial Genome Replication´´ is explained. Section one is about ‘‘Bacterial DNA History’’. Educator illustrates the evidence of DNA as a genetic material. After that Griffith's transformation experiments are discussed. Then experiments of Oswald Avery and colleagues are reported. The Hershey-Chase experiment are explained later.
Nucleic Acid and Protein Structure
Section two is about ‘’Nucleic Acid and Protein Structure’’. At first information is delivered on bacterial DNA. Then DNA structure is exhibited. Moreover, supercoiling in DNA is pursued. After that RNA structure is illustrated. Subsequently, protein structure comes under consideration.
Replication Initiation and Machinery
Section three is about ‘’Replication Initiation and Machinery’’. Educator started this section by explaining the accuracy of replication. After that initiation of replication is discussed. Then elucidation of replication machinery is given. Lastly, educator tells about the requirements of DNA polymerase.
Replisome and Events at Replication Fork
Section four is about ‘’Replisome and Events at Replication Fork’’. Initially, DNA polymerase III is thoroughly discussed. Next focus is on the composition of replisome. This is followed by the synthesis of leading and lagging strands. Lastly, events at the replication fork are pursued.
Completion and Termination of Replication
Section five is about ‘’Completion and Termination of Replication’’. Educator’s prime focus here is the removal of RNA primers. Next is the joining of Okazaki Fragments. Afterwards, educator elucidates that DNA polymerase III proofreading process takes place. Moreover, information is revealed about termination of replication. Finally, replication of linear chromosomes is highlighted.